Comparison of prostaglandin analogue, beta-blockers and prostaglandin analogue/beta-blockers fixed combination in patients with primary open-angle glaucoma
نویسندگان
چکیده
منابع مشابه
Fixed combination of travoprost and timolol maleate reduces intraocular pressure in Japanese patients with primary open-angle glaucoma or ocular hypertension: analysis by prostaglandin analogue
BACKGROUND We have shown a decrease in mean intraocular pressure (IOP) by switching to travoprost/timolol fixed combination (TTFC) in subjects receiving prostaglandin analogue (PGA) monotherapy and requiring additional medication in a previous report. For analyzing factors affecting IOP reduction, baseline IOP and preceding PGA were selected as statistically and clinically significant factors. ...
متن کاملComparison of b-Blockers and Prostaglandins Treatments in Primary Open-Angle Glaucoma
The main protective element of ganglion cells in hypertensive glaucoma is the reduction of intraocular pressure (IOP) [1]. IOP can be reduced in various ways. At present, the most commonly used drugs are β-blockers and prostaglandins. The study of Holmstrom et al [6], who observed the cost-effectiveness of bimatoprost, latanoprost and timolol in treatment of primary open angle glaucoma in five ...
متن کاملAqueous Humor Levels of Soluble Fas and Fas-ligand in Patients with Primary Open Angle and Pseudoex-foliation Glaucoma
Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...
متن کاملShould beta blockers be abandoned as initial monotherapy in chronic open angle glaucoma? The controversy.
βBlockers lower intraocular pressure (IOP) by reducing the rate of aqueous inflow. Shortly after the commercial release of topical timolol maleate in 1978 it became the most widely used ocular hypotensive agent. Its potency, combined with its twice daily frequency of instillation and lack of induction of miosis or accommodative spasm, was seen as a major advantage. Timolol was considered a revo...
متن کاملA 7 year prospective comparative study of three topical beta blockers in the management of primary open angle glaucoma.
AIM To determine the long term efficacy of monotherapy with topically applied beta blocking agents and to determine whether selective beta blockers were able to preserve the visual field more effectively than non-selective agents. METHOD A prospective randomised, open, comparative study of three topically applied beta blockers-timolol, betaxolol, and carteolol-was carried out on 153 patients ...
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ژورنال
عنوان ژورنال: Spektrum der Augenheilkunde
سال: 2013
ISSN: 0930-4282,1613-7523
DOI: 10.1007/s00717-013-0189-y